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AesculaTech engages in the development and manufacture of a platform of temperature-responsive smart materials for use in medical devices.
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Our first product is a punctual
plug for the treatment for
dry eye syndrome.

Problem

25% of visits to Ophthalmology clinics are due to dry eye syndrome and 64 million Americans are using over the counter eye lubricants more than 5x per week. However, 40 million of those patients report that eye drops are ineffective. This leads to 5 million patients undergoing a treatment known as punctal occlusion. Punctal occlusion physically blocks the tear duct, the drainage path for tears, using a punctal plug. This one-time treatment provides rapid symptom relief for 80% of patients, but 50% of plugs fall out within 6 months.

Solution

To address this problem, we have developed a shape-adaptive punctal plug. The plug is administered as a liquid and solidifies once inserted into the patient, adapting to their unique anatomy. The device is one‑size-fits-all and easy to administer, resulting in improved patient comfort and fewer repeat procedures.

Team

Andrew Bartynsky, PhD

CEO

Chemical
Engineering

Niki Bayat, Phd

CSO

Chemical
Engineering

Jose Ramírez, MS

PM

Bioengineering

Natalie Afshari, MD

Clinical Advisors

UC San Diego

Reza Dana, MD

Clinical Advisors

Harvard

Mark Thompson, PhD

Scientific Advisor

USC

Dimitri Villard

Advisor

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